SUFRE-Tulle* FRAMYCETIN SULPHATE
BP 1% Sterile Tulle bandages (10cm x 10cm and Roll Size as per customer demand)
is a prescription product: by or on the order of a physician. This product is
NOT being offered for sale to end users/patients in any country. It is being
offered to companies interested in carrying the product in their respective
portfolios and markets. It is not offered in markets where enforceable patents
manufactured in a fully GMP production facility and is backed by full quality
documentation. It consists of a cotton leno-weave fabric, impregnated with a
base composed of white soft paraffin, anhydrous lanolin, and 1.0% w/w
is an antibiotic of the aminoglycoside group with a wide spectrum of
antibacterial activity. Organisms sensitive to framycetin include
Staphylococcus aureus, Escherischia coli, Klebsiella species, and some strains
of Pseudomonas aeruginosa; it is not active against yeasts, fungi or viruses.
dressing is used as a primary wound contact layer in the management of infected
wounds, combining low adherence with antimicrobial activity.
may be used in the management of wounds, including minor traumatic injuries,
ulcers, burns, and other lesions that are clinically infected by organisms
shown to be sensitive to framycetin.
is contra-indicated in patients who are allergic to lanolin, or who have
previously demonstrated a sensitivity to framycetin, neomycin, or any other
chemically related product. The dressing should not be used in the treatment of
wounds that are free of clinical infection, or infected by organisms that are
resistant to the antibiotic.
METHODS OF USE
wound should be cleansed with a suitable sterile solution, such as normal
saline; a single layer of SUFRE-Tulle should then be applied and covered with
an absorbent pad, held in place
tape or a bandage, as appropriate. When used to dress ulcers, SUFRE-Tulle*
should be shaped to fit the crater and not allowed to extend over the
SULPHATE Details used in SUFRE-TULLE as Antibiotic.
Sulphate is an antibiotic, belonging to the Aminoglycoside group, with
bactericidal effect with a wide antibacterial spectrum. The mechanism of action
of framycetin appears to be related to inhibition of bacterial protein
synthesis via binding to ribosomal subunits.
is active against Staphylococcus spp., including coagulase-negative
Staphylococci, Escherichia coli, Klebsiella spp., Salmonella, Shigella,
Enterobacter spp., Proteus spp., Serratia marcescens, Pasteurella spp., Vibrio
spp., Borellia and Leptospira spp. and Mycobacterium tuberculosis including
also Streptomycin-resistant strains. Framycetin shows comparatively high
activity against some strains of Pseudomonas aeruginosa, which is a main
resistance to framycetin is hardly achieved after often and very prolonged use.
For avoidance the occurrence of resistance or with reference to the extension
of the therapeutic spectrum, usually in drug forms with framycetin are included
other antibacterial agents, as well as steroid antiphlogistics. In
dermatological practice framycetin is administered for treatment of wounds,
ulcers, burns and other skin defects, infected with susceptible
microorgan¬isms. The antibiotic is preferred agent for treatment of bacterial
dermatoses and pyodermes as impetigo, furunculosis etc.
ophthalmology the antibiotic is successfully applied for treatment of
con¬junctivas, blepharitis and infections of the front ocular segments. The
topical forms with framycetin manifest high effect at the treatment of corneal
ulcers. In spite of the possible manifestation of ototoxicity Framycetin
Sulphate alone or in combination with other antibacterial or anti-inflammatory
agents is used also for preparation of ear drops. With reference to the wide
usage of framycetin in otorhinolaryngology and the single incidents, it is
accepted that the ototoxicity risks are insignificant after topical
application. Topical forms containing framycetin are successfully used at the
treatment of rhinitis caused by Staphylococci.
- Availability: In Stock